- According to new research funded by ‘Breast Cancer Now’ at the University of Manchester, scientists have identified RAC1B as a potential way of improving treatment for breast cancer.
- RAC1 is a vital protein that plays an important role in maintaining the health of all organs.
- These findings were published in "Oncogene," which says breast cancer stem cells that are thought to cause cancer’s resistance to treatment, recurrence, and spread rely on RAC1B.
- The absence of RAC1B protein in the cells of the body makes it an attractive target for future breast cancer treatment.
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- The research was performed on mice when breast cancer cells were injected into mice, and it was found that cancer cells lacking RAC1B formed no visible tumours even after 100 days.
- Further investigations also showed that breast cancer cells that grow in the lab without RAC1B didn't recover after being treated with the chemotherapy drug doxorubicin.
- The study has shown that without RAC1B, breast cancer stem cells cannot form tumours and become more vulnerable to chemotherapy, which makes the treatment even more effective.
- Further research into this topic will help find targeted therapies for breast cancer patients.
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Source- News Medical