Dr. Partha Sarathi Das is one of the well-known and very prominent Infertility specialists in UAE. At present, he is working as a consultant at Orchid Fertility Clinic Dubai. With his praiseworthy experience of more than 15 years his proficiency lies in the treatment of Implantation failure, PCOS, the immunological basis of infertility, PGD/PGS, fertility preservation in cancer patients, IVF, Gynae Problems, Fertility Conserving Procedures, Fertility Treatment, and Endometrial receptivity. His education qualification includes graduation and post-graduation from a reputed university in India. Followed by his master's in assisted reproduction from the prestigious University of Valencia Spain. He is an esteemed member of the European Society for Human Reproduction and Embryology and American Society for Reproductive Medicine. He has publications contributed to international as well as national journals. He is all-over invited as a guest speaker in scientific conferences, CDE's, and worldwide conferences.
Implantation Failure
It refers to the inability to achieve pregnancy due to the embryo that was once fertilized by the union of egg and sperm and now has failed to stay in the uterine wall to form the gestational sac. It is very difficult to detect the cause of infertility in a couple. It may be due to implantation failures or while trying to conceive naturally as it is not possible to know. Implantation failure occurs when the embryo is not ready to synchronize with and fasten the endometrium.
Specifically, implantation failure is considered to exist when the woman has not achieved pregnancy after three complete IVF cycles. It is said to be failed when it has not made women pregnant with the transfer of about 6 or more embryos and 2 egg donation cycles.
Causes
- Embryonic Causes
Genetic alterations in the embryo or the gametes of the progenitors, or in the zona pellucida of the embryo that prevent hatching.
- Uterine Causes
Endometriosis adhesions, uterine malformations, hydrosalpinx, infections, endometrial polyps, fibroids, etc.
- Systemic Causes
Thrombophilias, endocrine alterations, autoimmune diseases
Diagnosis and Treatment
To increase the likelihood of pregnancy a series of tests must be carried out before effective treatment can be applied. The diagnosis of implantation failure is difficult. But the result of these tests generally helps the specialists to personalize fertility treatment as much as they can.
Studies Of Thyroid Clotting or Function
- Immunomodulation test for immune rejection
Parent Karyotype
- Hysteroscopy or hysterosalpingography to look at the cavity
- Endometrial biopsy to study endometrial receptivity
Treatment
Depending on the results of these tests and the most probable cause of the failure to implant the embryos in the uterus is detected. The appropriate treatment is then outlined and provided.
- Preimplantation Genetic Diagnosis
- Extended culture to blastocyst
- Surgical techniques
- Endometrial Receptivity Analysis
- Pharmacological treatment
- Egg and Embryo Donation
- Surrogacy
Take Away
Your doctor will diagnose and discuss the cause of Implantation failure. Depending on this treatment the doctor will choose one measure from the above. For detailed discussion and treatment, you can consult Dr. Partha Sarathi Das one of the best Infertility Specialists in Dubai. You can meet him at Orchid Fertility Clinic Dubai.
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