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Prof. Dr. Steffen U. Eisenhardt
4.7 (16 Ratings)
Cosmetic Surgeon
Freiburg University Hospital, Freiburg · Freiburg
19+ years of experience
About Prof. Dr. Leena Bruckner-Tuderman
- Prof. Dr. Leena Bruckner-Tuderman is a well-experienced Dermatologist with more than 32 years of experience.
- She is an active member of various organizations including the Swiss Society for Dermatology and Venereology, Zurich Dermatologists' Society, German Dermatological Society (DDG), European Society for Dermatological Research (ESDR), European Academy of Dermatology and Venereology, Society for Investigative Dermatology, USA, etc.
- She completed her Medical School and academic dissertation from the University of Oulu, Finland in 1971, and Postdoctoral research training from Rutgers Medical School, N.J. USA and Biocenter, University of Basel, Switzerland.
- She also has a Heisenberg Fellowship from the German Research Foundation (DFG) in 1994.
- Her area of expertise includes Cryotherapy, Laser, Cosmetic Dermatology, Dermatologic Surgery Electrocautery, Dermatoscopy, Allergic Skin Diseases, Skin Tumours, Botox & Skin Rejuvenation, etc.
- Dr. Leena has written up to 100 local and foreign publications and participated in 50 congresses and symposiums.
Location
MD, University of Oulu, Finland(1977)- Graduation, University of Muenster, Germany (in the EU)(1995)
- Fellowship, Fellowship, Rutgers Medical School, Piscataway, NJ, USA(1977)
- Fellowship, Fellowship, Biocenter, University Basel, Switzerland(1980)
2017: Honorary doctorate, University of Oulu, Finland
2017: Honorary doctorate, Semmelweis University, Budapest, Hungary
2014: Distinguished Investigator Award, International Society of Matrix Biology
2009: Eva Luise Köhler Prize for Research on Rare Diseases
2009: Chair, Gordon Research Conference “Collagens”
2008: Rudi Cormane Lecture, European Society for Dermatological Research
2007: Maria Duran Lectureship from the International Society for Dermatology
2002: Chair, Gordon Research Conference “Basement membranes”
- Visiting Consultant, University Hospital Zurich and University Hospital Münster
- Senior Resident, University Hospital Zurich, Switzerland
Papers Published
- C. Has, G. Sparta, D. Kiritsi, L. Weibel, A. Moeller, V. Vega-Warner, A. Waters, Y. He, Y. Anikster, P. Esser, B.K. Straub, I. Hausser, D. Bockenhauer, B. Dekel, F. Hildebrandt, L. Bruckner-Tuderman, G.F. Laube: Integrin alpha3 mutations with kidney, lung, and skin disease. New Engl J Med, 2012; 366 (16): 1508-1514.
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- C.W. Franzke, C. Cobzaru, A. Triantafyllopoulou, S. Loffek, K. Horiuchi, D.W. Threadgill, T. Kurz, N. van Rooijen, L. Bruckner-Tuderman, C.P.Blobel: Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med, 2012.
- D. Kiritsi, Y. He, A. M.G. Pasmooij, M. Onder, R. Happle, M. Jonkman, L. Bruckner-Tuderman, C. Has: Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination. J Clin Invest. 2012; 122(5): 1742-1746.
- L.Y. Chiang, K. Poole, B.E. Oliveira, N. Duarte, Y.A. Sierra, L. Bruckner-Tuderman, M. Koch, J. Hu, G.R. Lewin: Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons. Nat Neurosci, 2011 (14): 993-1000.
- W. Nishie, D. Kiritsi, A. Nystroem, S.C. Hofmann, L. Bruckner-Tuderman: Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partner. Am J Pathol, 2011 (179): 829-837.
- Y. He, P. Esser, A. Heinemann, L. Bruckner-Tuderman, C. Has: Kindlin-1 and-2 Have Overlapping Functions in Epithelial Cells Implications for Phenotype Modification. Am J Pathol, 2011; 178 (3): 975-982.
- W. Nishie, S. Lamer, A. Schlosser, E. Licarete, C.-W. Franzke, S.C. Hofmann, J. Jackow, C. Sitaru, L. Bruckner-Tuderman: Ectodomain shedding generates neoepitopes on collagen XVII: role in autoimmune blistering diseases. J Immunol, 2010 (185):4938-47.
- L. Bruckner-Tuderman: Systemic Therapy for Genetic Skin Disease. New England Journal of Medicine, 2010; 363 (7): 680-682.
- A. Sprenger, V. Küttner, M.L. Biniossek, C. Gretzmeier, M. Boerries, C. Mack, C. Has, L. Bruckner-Tuderman, J. Dengjel: Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications. Molecular Biosystems, 2010; 6 (9): 1579-1582.
- A. Sprenger, V. Küttner, M. Biniossek, C. Gretzmeier, C. Mack, C. Has, L. Bruckner-Tuderman, J. Dengjel: Primary human cells for clinical disease proteomics. Molecular Biosystems, 2010; 6: 1579-1582.
- J.S. Kern, S. Loeckermann, A. Fritsch, I. Hausser, M.L. Müller, O. Paul, P. Ruther, L. Bruckner-Tuderman: Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Mol Therapy 17, 1605-15, 2009.
- C. Franzke, L. Bruckner-Tuderman, C. Blobel: Shedding of collagen XVII/BP180 in the skin depends on both ADAM10 and ADAM9. Journal of Biological Chemistry, 2009; 284 (35): 23386-23396.
- A. Fritsch, S. Spassov, S. Elfert, A. Schlosser, Y. Gache, G. Meneguzzi, L. Bruckner-Tuderman: Dominant-negative effects of COL7A1 mutations can be rescued by controlled overexpression of normal collagen. J Biol Chem, 2009; VII (284): 30248-30256.
- A. Fritsch, S. Loeckermann, J.S. Kern, A. Braun, M.R. Bösl, T. Bley, H. Schumann, D. von Elverfeldt, D. Paul, M. Erlacher, D. Berens von Rautenfeld, I. Hausser, R. Fässler, L. Bruckner-Tuderman: A hypomorphic mouse model for dystrophic epidermolysis bullosa reveals disease mechanisms and responds to fibroblast therapy. J Clin Invest, 2008 (118): 1669-1679.
- J.S. Kern, C. Herz, E. Haan, D. Moore, S. Nottelmann, T. von Lilien, P. Greiner, A. Schmitt-Graeff, O.G. Opitz, L. Bruckner-Tuderman, C. Has: Chronic colitis due to epithelial barrier defect: role of kindlin-1 isoforms. J Pathol, 2007 (213): 462-470.
- E. Zimina, A. Fritsch, B. Schermer, A. Bakulina, M. Bashkurov, T. Benzing, L. Bruckner-Tuderman: Extracellular phosphorylation of collagen XVII by casein kinase 2 inhibits ectodomain shedding. J Biol Chem, 2007 (282): 22737-22746.
- C.-W. Franzke, K. Tasanen, L. Borradori, V. Huotari, L. Bruckner-Tuderman: Shedding of collagen XVII/BP180: structural motifs influence cleavage from the cell surface. J Biol Chem, 2004 (279): 24521-24529.
- K. Tasanen, L. Tunggal, G. Chometon, L. Bruckner-Tuderman, M. Aumailley: Keratinocytes from patients lacking collagen XVII display a migratory phenotype. Am J Pathol., 2004 (164): 2027-2038.
- C. Baldeschi, Y. Gache, A. Rattenholl, P. Bouillé, O. Danos, J.-P. Ortonne, L. Bruckner-Tuderman, G. Meneguzzi: Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors. Human Molec Genet, 2003 (12): 1897-1905.
- C.-W. Franzke, K. Tasanen, H. Schäcke, Z. Zhou, K. Tryggvason, C. Mauch, P. Zigrino, S. Sunnarborg, D.C. Lee, F. Fahrenholz, L. Bruckner-Tuderman: Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs. EMBO, 2002 (J 21): 5026-5035.
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Where does Prof. Dr. Leena Bruckner-Tuderman practice?
Prof. Dr. Leena Bruckner-Tuderman practices at Freiburg University Hospital, Freiburg
What is the specialty of Prof. Dr. Leena Bruckner-Tuderman?
Prof. Dr. Leena Bruckner-Tuderman specialty is Hair Transplant Specialist
What is the experience of Prof. Dr. Leena Bruckner-Tuderman?
Prof. Dr. Leena Bruckner-Tuderman is Hair Transplant Specialist with 40 years of experience.
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