Pediatric Myelodysplastic Syndrome Mds Treatment Treatment Cost In Chennai

Myelodysplastic syndromes are a group of rare disorders in children in which the bone marrow does not make enough healthy blood cells, pediatric MDS is different than adults.

MDS is very rarely seen in children around 1 million children are being diagnosed with MDS every year. Patients with MDS are less than 5% of total pediatric cancer.

The cause of MDs is not known but some of the causes of MDs includes any previous treatment with radiotherapy and chemotherapy, previous aplastic anemia, inherited genetic mutations, inherited bone marrow failure syndrome, congentia neutropenia.

Symptoms are not noticed in the early stages of disease, MDS is usually seen on blood tests because of low blood cell counts. The symptoms of MDS can vary from person to person some of the symptoms seen are anemia, feeling of tiredness, shortness of breath, pale skin, fever and weight loss.

The prognosis of MDS is varies according to the specific feature of the disease, the availability of the bone marrow transplant donor. In some children MDS can be cured with bone marrow transplant while some children only need transfusion.

Many children who have MDS can remain stable for years and don’t need any therapy, these children should be closely checked by experienced hematologist and they should need follow up.

The rate of progression of MDS varies , in some patients the condition gets worsen within few months of diagnosis while other people may have very little problem for years. In about 50 percent patient the condition deteriorates and form a cancer known as  acute myeloid leukemia.

For children pediatrician checks for the disease and if they notice something is wrong then they will send them to the specialist.

The best and the most effective treatment for MDS is bone marrow transplant. In this procedure person receives healthy bone marrow from the donor such as from their own sibling or an unrelated donor from a donor bank or parent.

In the first step blood is collected from patient bone marrow or peripheral blood.  Bone marrow or the blood is being processed in the laboratory to isolate, prepare and concentrate stem cells.  Stem cells are preserved at very low temperature in protective solution to keep the stem cells alive until it is ready for transportation. Patient are treated with chemotherapy or radiation therapy to destroy cancer cells and at last stem cells are rein fused in patients bone.

Some of the tests needed after MDS are needed to diagnose cancer cells and to find out which stage of cancer can be repeated. Some of the test may be repeated to check how the treatment is working. The decision about the treatment is based on the result of these tests.

Some precautions which should be taken into consideration include palliative care which focuses on reducing the symptoms and improving the quality of life.  It should be started early as it is needed in treatment process. MDS treatment improves the quality of life reduces the symptoms.

Recurrence of MDS can either be temporary or permanent, in some cases the remission is long last so it is important for you to talk to the doctor about the recurrence of the disease and treatment options.  If you understand the risk of recurrence you may feel more prepare about the disease if it does not return.

To recover from MDS is not possible in every case. If MDS can’t be controlled or cured it is called advance or terminal treatment.  You should discuss  with your doctor about your concern, the healthcare team is always ready to help.