Lu177-PSMA therapy is also known as Prostate-Specific Membrane Antigen Therapy. The treatment is a successful way to reduce the tumor's size and also stop them from multiplying. It is a popular treatment choice for men with advanced prostate cancer.
PSMA is a type of protein shown on the membrane of prostate cells. Lutetium is a radiation-based treatment that utilizes a molecule to attach itself to the PSMA receptors located on the cancer cells. Lu-177 emits beta radiation to damage cancer cells. The Lutetium molecule binds with the PSMA by targeting the molecules of PSMA, and the treatment becomes very precise.
The Lu-177 PSMA is administered intravenously through a catheter. Once it enters the body, it travels throughout the bloodstream to find the area with active prostate cancer growth and gets attached to the PSMA receptor. After that, it delivers the radiation directly into the nucleus of those cells. The radiation used in Lu-177 is designed only to destroy cancer cells, and the whole body is never exposed to the radiation.
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The success rate varies between 64% to 75%.
It is recommended to have three treatments, but a single treatment may be enough.
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