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US Surgeons Perform the First Pig-to-Human Kidney Transplant

  • A 62-year-old male with end-stage renal disease became the first human to receive a new kidney from a genetically modified pig.
  • The surgery performed on March 16, 2024, took four hours and is a major milestone in the search to make organs more readily available to patients.
  • The hospital said the patient is recovering well and expected to be discharged soon.
  • The patient received a human kidney transplant at the same hospital in 2018 after seven years of dialysis, but the organ failed after five years, and he resumed dialysis treatments.
  • The pig kidney provided by eGenesis of Cambridge, Massachusetts, had been genetically edited to remove genes harmful to a human recipient and add certain human genes to improve compatibility. 
  • The company also inactivated viruses inherent to pigs that could infect humans.
  • Drugs used to help prevent rejection of the pig organ by the patient's immune system included an experimental antibody called tegoprubart developed by Eledon Pharmaceuticals.
  • Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, said the surgery marks progress in xenotransplantation (the transplanting of organs or tissues from one species to another).

Source: Heathworld, Reuters

Author Name
Nishu Negi

Published Date
: 22-Mar-2024

A microbiologist by education, Nishu Negi clearly understands scientific/healthcare concepts and ideas. She is a creative content writer passionate about innovative concepts and expresses these with clarity in her writing. She enjoys writing blog posts and articles in a way that the target audience understands them. 

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