Lutetium-177–PSMA is a radiotherapy that targets prostate cancer cells (while limiting most normal tissues) using imaging to confirm radionuclide binding. Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer cells. High PSMA expression has been independently associated with reduced survival.
Lu-177-PSMA therapy is associated with reduced pain and low toxicity in patients with metastatic castration-resistant prostate cancer progression after standard therapy.
First, Lu PSMA is applied by slow intravenous injection (30–60 sec) followed by a sterile 0.9% sodium chloride flush.
Then, to attach itself to the PSMA receptors on the cancer cells, the radiation based-treatment utilizes a molecule. By targeting the molecules of PSMA, the radiation-focused treatment by Lu becomes very precise as the Lu molecule binds with the PSMA.
Lu-177 emits beta radiation that effectively damages cancer cells and, over time, destroys them.
An Oncologist is the right doctor to perform this procedure.
The cost of Lutetium 177-PSMA includes:
The overall cost of the procedure also varies based on the patient's condition and preferences. Some of these factors are:
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30-70% of men were reported with > 50% reduction in serum PSA levels after the procedure.
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