Request a Quote
English Arabic French Russian

Woman with Oncogene Gave Birth to Twins without the Mutation

Eight years ago, Bengaluru’s Swayam Prabha came to know that she carries the cancer-causing BRCA1 mutation and was tensed about not passing on the oncogene to children. With the help of modern medical techniques, she gave birth to twins in Jaslok Hospital who don’t carry the mutation- the first case of its kind in the country.


“My mother has cancer and her sisters passed away due to this. I have BRCA1 (BReast CAncer gene) mutation but this cancer cycle will end with me. My children have been spared,” said 37-year-old Swayam.


In Swayam’s case, IVF specialist Dr. Firuza Parikh and her team screened the embryos for the absence of BRCA1 mutation. The pre-implantation genetic tests were done and embryos without BRCA1 mutation were transferred into the womb.


“With IVF, we managed six embryos for Swayam. While two carried the mutation and the remaining two didn’t”, said Dr. Parikh. She added,”Swayam’s case is the first in India where the threat posed by oncogenes was removed. PGT (Preimplantation Genetic Testing) has been used to keep out BRAC1 and BRAC 2 genes in roughly 150 cases worldwide.”


“My mother’s sisters, cousins and uncle had cancer. Doctors at Tata Memorial Centre in Parel asked me and my siblings to undergo genetic test for oncogenes,” said Swayam.


Procedure of Pre-Implantation Genetic Testing (PGT)

PGT is used prior to implantation to identify genetic defects in embryos. The steps involved in Preimplantation Genetic Diagnosis are:

  1. Cells are microsurgically removed from 5 days developed embryos. After this, embryos are frozen.
  2. DNA of cells is done to determine if there’s problematic gene in each embryo. This process takes at least 5-7 days.
  3. Once embryos free of genetic problems are identified, it will be placed in the uterus.
  4. Additional embryos which are free of genetic problems are frozen for later use while embryos with the problematic gene are destroyed.
Author Name
Manpreet Kaur

Published Date
: 30-Jul-2018

Manpreet Kaur is an Engineer by education but found her interests in research and writing. Her prolific career spans the world of health, travel and digital marketing. She is a music lover who can be found with headphones on at any time of the day. If not found in office, then it is for sure she had packed her bag and is on trip to quench her thirst for adventure.

Trying to extract the best out of life, she has eclectic mind trapped in a peripatetic body.

Share Articles

Need Help?

Just let us know. We will be happy to assist you

To overcome restrictions due to Corona Virus, we are offering Paid Tele/Video Consultation from top doctors. Let us know if you are interested & we will contact you.

After submitting the form, check your email for instructions to share patient information and medical reports.




About Vaidam

Patients from 85+ countries have trusted Vaidam


Why Vaidam


NABH Certified Healthcare Discovery Platform

Vaidam is NABH certified healthcare discovery platform that will connect you to top-notch medical experts, hospitals, wellness options, and trusted travel partners to help identify and make the right healthcare choices.

Researched & Personalized Treatment Plan - Under One Roof

You can search for the best hospitals in India to treat cancer and ailments of the heart, bones or kidney, read about them, view photographs of the facilities at the hospitals and the places at which the hospitals are located, and check the cost of treatment.

Quality Treatment Within Your Budget

As soon as you post an enquiry, the patient relation team will collect details from you, share them with the doctors and hospitals on Vaidam's panel, and get a personalized treatment plan. We research to get quality treatment within your budget.

Treatment to Travel

Vaidam concierge assists patients, to get medical Visa to travel to India, the best airline fares and arrangements for your stay. Our concierge also helps you with daily travel, language, and food concerns. Vaidam does everything to be your perfect host. All of Vaidam’s services are free of cost to patients.

International Reach

If you are looking for medical care in India (New Delhi, Mumbai, Chennai, Hyderabad or Ahmedabad) or in Turkey (Istanbul,Ankara or Antalya), Vaidam Health has a network in each of those cities.

Vaidam News


Vaidam Health gets the prestigious NABH accreditation

Vaidam Health gets the prestigious NABH accreditation

Read more

Vaidam Media - Medical Travel Today

Vaidam Health Coverage by Medical Travel Today - The Authoritative Newsletter for Medical Tourism

Read more

Vaidam Health YourStory News

Vaidam Health gets covered by 'Your Story', India's Leading Online Magazine

Read more

Know how it works in less than 90 secs

View More Updates




Note: Vaidam Health does not provide medical advice, diagnosis or treatment. The services and information offered on are intended solely for informational purposes and cannot replace the professional consultation or treatment by a physician. Vaidam Health discourages copying, cloning of its webpages and its content and it will follow the legal procedures to protect its intellectual property


Browse the website in:   English     Français   Русский     العَرَبِية



Thank you. We will contact you soon.