A bone marrow transplant is a medical procedure done to replace the damaged bone marrow with a healthy one. The damaged bone marrow may be damaged by infection, chemotherapy or any other disease. The transplant is done by transplantation of stem cells in the blood. The stem cells travel to the bone marrow and produce new blood cells to promote the growth of new bone marrow.
The bone marrow transplant cost in India is very reasonable with state-of-the-art technology and work with the best experts to give a high success rate
What conditions require a bone marrow transplant?
The bone marrow transplant is usually required for the following reasons:
Replacement of diseased and non-functioning bone marrow with healthy bone marrow that functions well.
Replacement of the bone marrow to restore the normal function after high doses of chemotherapy or radiotherapy given to treat malignancy.
Regeneration of the immune system to fight existing or residual leukemia or other cancer, which were not treated by chemotherapy or radiation used in the transplant.
Replacement with a bone marrow that is genetically healthy functioning to prevent any damage from a genetic disease process.
What happens after the bone marrow transplant?
Once the transplant is finished, the patient needs to stay in the hospital for a few weeks to wait for the stem cells to settle in the bone marrow and start producing new blood cells. In the hospital, the patient will be isolated because of the increased risk of infection. The team of doctors will closely monitor the blood count and vital signs.
The duration of stay in the hospital depends on:
How much chemotherapy or radiation the patient has received
The type of transplant performed
Before the discharge, the doctor will make sure
Bone marrow is making enough healthy blood cells
The patient has no severe complications
Patient feel well and any mouth sores and/or diarrhea have improved or gone away
Appetite has improved
There is no fever or vomiting
During the hospital stay patient might:
Feel weak, and may experience vomiting, diarrhea and/or a loss of appetite
Receive medicines to prevent or treat infections, including antibiotics, antifungals, and antiviral medicine
Need many blood transfusions, because of a low number of red blood cells
Have regular platelet transfusions because of a low number of platelets
Be fed through a vein until you can eat by mouth and stomach side effects and mouth sores have gone away
How much time does it take to recover from a Bone Marrow Transplant?
During the first weeks and months after leaving the hospital, the patient will have to make frequent trips to an outpatient clinic. This will allow doctors to track the patient’s progress. These visits will become less often over time.
Staff at the clinic will teach the patient and their caregiver how to care for your central line (which will stay in place for at least 6 months after your transplant), how to watch for and prevent infections, and other ways to care
Recovery from a stem cell transplant can be slow. It takes 6 to 12 months to recover normal blood cell levels and immune function. During this time, it's important to take steps to reduce the risk of infection, get plenty of rest, and follow the doctor’s instructions about medicines and checkups.
What is the life expectancy after a bone marrow transplant?
People with a bone marrow transplant, who are able to survive for at least 5 years after hematopoietic cell transplant without any signs and symptoms of relapse of the original disease, have more probability of surviving for another 15 years. However, a normal life expectancy is not completely achieved.
Despite a very high success rate of this procedure, there are chances of several types of complications. These complications may vary from patient to patient depending upon various factors such as,
Age and overall health of the patient
Any underlying disease and its chances of recurrence
Presence of any other medical condition
Type of transplant
Preparations are done before the transplant
The health of the donor
To read in detail about the risks and complications associated with a bone marrow transplant click here.