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Aplastic Anemia Treatment and Cost in India

Consider the Best Opinions For the Rarest of Health Complications

  • Depending on treatment option and the type of disease, the average cost of Aplastic Anemia Treatment in India ranges between USD 29000 to USD 30000.
  • The various treatment options available are Cyclophosphamide Drug Therapy, Blood Transfusions, Bone Marrow Transplantation and Drug Therapy.
  • Patient has to spend 10 days in hospital and 28 days outside the hospital.
  • Tests required to diagnose Aplastic Anemia are Blood tests and Bone Marrow Biopsy.

Aplastic Anemia Treatment and Cost in India

Consider the Best Opinions For the Rarest of Health Complications

 

  • Depending on treatment option and the type of disease, the average cost of Aplastic Anemia Treatment in India ranges between USD 29000 to USD 30000.
  • The various treatment options available are Cyclophosphamide Drug Therapy, Blood Transfusions, Bone Marrow Transplantation and Drug Therapy.
  • Patient has to spend 10 days in hospital and 28 days outside the hospital.
  • Tests required to diagnose Aplastic Anemia are Blood tests and Bone Marrow Biopsy.

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Aplastic Anemia Treatment Cost In India

Aplastic Anemia Treatment Price USD 29,000 No. of Travellers 2 Days in Hospital 10 Days Outside Hospital 28 Total days in India 38
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Top Doctors For Aplastic Anemia Treatment in India View all (16)

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Selected :
Doctor for Aplastic Anemia - Dr. TPR Bharadwaj

Dr. TPR Bharadwaj

Hematologist

43 years of experience , Chennai

Doctor for Aplastic Anemia - Dr. Anil Handoo

Dr. Anil Handoo

Hematologist

10 years of experience , New Delhi

Doctor for Aplastic Anemia - Dr. Srikanth M

Dr. Srikanth M

Hematologist

21 years of experience , Chennai

Doctor for Aplastic Anemia - Dr. Manas Kalra

Dr. Manas Kalra

Hematologist

13 years of experience , New Delhi

More About Aplastic Anemia

Aplastic Anemia occurs due to the inability of the bone marrow to produce new blood cells. People suffering from this medical condition have a higher risk of infections and uncontrolled bleeding. Aplastic Anemia can occur at any age and is a rare but serious condition. This disease can occur suddenly or gradually develop into a more serious condition.

Aplastic Anemia, in most cases, is an acquired disease, but in some cases, it may be inherited from parents. According to studies, it is an autoimmune disorder, a medical anomaly in the body which causes the body’s immune system to attack its own tissues and organs. Though Aplastic Anemia is not cancer, the treatment modalities are similar to that those of leukemias and lymphomas, which are types of blood cancers. Some of the treatment options for this disease include drugs, stem cell transplant or bone marrow transplant, and blood transfusions.

 

Symptoms of Aplastic Anemia

Following are the symptoms of Aplastic Anemia:

  • Rapid and irregular heartbeat or heart rate
  • Fatigue
  • Paleness of skin or skin rashes
  • Difficulty in breathing after minor exertion
  • Continuous bleeding from minor cuts
  • Recurring and prolonged infections
  • Headaches and dizziness

 

Causes of Aplastic Anemia

When your bone marrow slows down or totally shuts down the new blood cell production, Aplastic Anemia develops. The stem cells found in the bone marrow are responsible for producing blood cells, including red blood cells, white blood cells and platelets. In medical terms, aplastic means something that is empty which refers to the bone marrow in Aplastic Anemia.

Aplastic Anemia may be caused due to temporary or permanent damage to the bone marrow thereby affecting blood cell production. Injury to the bone marrow may occur due to the following reasons:

  • Chemotherapy and Radiation treatment: These therapies are performed to fight and kill cancer cells but sometimes in the process, healthy cells such as stem cells that produce blood in the bone marrow may get damaged as well. However, they only cause Aplastic Anemia temporarily.
  • Toxic Chemicals Exposure: Exposure to toxic chemicals found in pesticides and insecticides, as well as benzene, can also lead to Aplastic Anemia. In such cases, once repeated exposure is avoided the illness may go on its own unless it has reached a chronic stage.
  • Drug Side Effects: Even some drugs, especially those used in treating rheumatoid arthritis and antibiotics, have been linked to Aplastic Anemia.
  • Autoimmune Disorders: Autoimmune disorders may also attack stem cells in the bone marrow to cause Aplastic Anemia.
  • Aplastic Anemia in Pregnancy: Some women suffer from Aplastic Anemia during pregnancy due to an autoimmune disorder.
  • Viral Infection: Some viruses such as Hepatitis, HIV, Parvovirus B19, Cytomegalovirus and Epstein-Barr have been linked to the development of Aplastic Anemia.
  • Chemotherapy and Radiation treatment: These therapies are performed to fight and kill cancer cells but sometimes in the process healthy cells such as stem cells that produce blood in the bone marrow may get damaged as well. However, they only cause Aplastic Anemia temporarily.
  • Toxic Chemicals Exposure: Exposure to toxic chemicals found in pesticides and insecticides, as well as benzene, can also lead to Aplastic Anemia. In such cases, once repeated exposure is avoided the illness may go on its own unless it has reached a chronic stage.
  • Drug Side Effects: Even some drugs, especially those used in treating rheumatoid arthritis and antibiotics, have been linked to Aplastic Anemia.
  • Autoimmune Disorders: Autoimmune disorders may also attack stem cells in the bone marrow to cause Aplastic Anemia.
  • Aplastic Anemia in Pregnancy: Some women suffer from Aplastic Anemia during pregnancy due to an autoimmune disorder.
  • Viral Infection: Some viruses such as Hepatitis, HIV, Parvovirus B19, Cytomegalovirus and Epstein-Barr have been linked to the development of Aplastic Anemia.

 

Diagnosis

Doctors diagnose Aplastic Anemia by examining blood and the cells of the bone marrow under a microscope. As this is a serious medical condition that warrants immediate medical attention, doctors will quickly perform blood and laboratory tests, including biopsy and bone marrow aspiration. The doctor will extract a sample of the bone marrow from the hipbone under local anesthesia to take the test. 

The test is carried out in the laboratory to analyze the following:

  • Number of blood cells, including platelets, neutrophils and reticulocytes
  • Kidney function
  • HLA-typing to ensure that the blood and marrow products received during the treatment are immune-system compatible

Ideally, the diagnosis should be performed by a senior bone marrow specialist. Plastic Anaemia is classified into three levels, including:

  • Moderate (MAA)
  • Severe (SAA)
  • Very Severe (VSAA)

 

Treatment Options

Treatment options for Aplastic Anemia patients depend upon the severity of the disease. While a moderate form of the disease has no standard of treatment, severe Aplastic Anemia is usually treated with bone marrow transplant or immune system suppression therapy. If a patient is younger than 40 years old and has a sibling with matching blood, bone marrow (stem cell) transplant is the usual form of treatment. For patients over 40 and without a sibling in the same blood group, drug therapy is the usual path taken for treatment.

The following treatment options are used in patients suffering from various stages and severity of Aplastic Anemia:

  • Cyclophosphamide Drug Therapy: For patients that cannot or are not required to go bone marrow transplant, they are treated with the chemotherapy drug cyclophosphamide to achieve remission and remove Aplastic Anemia causing cells. During this therapy, it is also ensured that the essential blood-producing stem cells are not destroyed.
  • Blood Transfusions: If patients are severely deficient in blood cells, ideally, blood platelet transfusions are the first course of treatment. These blood transfusions help overcome symptoms of Aplastic Anemia such as shortness of breath and fatigue. It also reduces the risk of hemorrhage which can be fatal in an Aplastic Anemia patient. Though this form of treatment may help quickly normalize the patient’s condition, long-term recovery is rarely achieved with this type of treatment.
  • Bone Marrow Transplantation: Also known as stem cell transplant, it is one of the most effective treatments for Aplastic Anemia. In this treatment, a bone marrow from a sibling or other family member is used to replace the malfunctioning bone marrow of the patient. The non-functional bone marrow in the patient is first destroyed by radiation or drugs before the transplant is performed. The new bone marrow from a donor is given intravenously to the patient. If the transplant goes successfully, it can often cure Aplastic Anemia and there are fewer chances of a relapse. In cases of severe or very severe Aplastic Anemia, bone marrow from unrelated donors may also be used if they are not responding to immunosuppressive drug therapy.
  • Drug Therapy: When bone marrow transplant may not be possible due to age, general health conditions or the unavailability of donors, immunosuppressive drug therapy may be the only option. This therapy is done using the drug, anti-thymocyte globulin (ATG) and cyclosporine. Drug therapy is good for partial restoration of blood cell production but not a permanent cure for Aplastic Anemia. 

 

Supportive Care

Supportive care is one of the crucial aspects of managing Aplastic Anemia in the long-term. For patients who require regular transfusions, a tube that helps the medicine reach directly to a vein in the chest for faster response (known as a central venous catheter) may be required. Also, packed red blood cells to correct or avoid cardiopulmonary complications must be kept handy for patients with blood element deficiencies. In addition, Aplastic Anemia patients require regular antibiotics or antiviral or antifungal agents to protect themselves from fungal and bacterial infections, a major cause of death among severe aplastic anemia patients.

 

 

 

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